MovDisordV3, Main, Exploration, bibRecord, 001224

A Study of Subtle Motor Signs in Early Parkinson's Disease

Identifieur interne : 001224 ( Main/Exploration ); précédent : 001223; suivant : 001225

A Study of Subtle Motor Signs in Early Parkinson's Disease

Auteurs : Susanne A. Schneider [Allemagne] ; Laura Drude [Allemagne] ; Meike Kasten [Allemagne] ; Christine Klein [Allemagne] ; Johann Hagenah [Allemagne]

Source :

Movement disorders [ 0885-3185 ] ; 2012.

RBID : Pascal:12-0423946

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Signe, Phase initiale, Echelle d'évaluation.

English descriptors

KwdEn :
- Early phase, Evaluation scale, Nervous system diseases, Parkinson disease, Sign.

Abstract

Background: The UPDRS is the most widely used rating scale for Parkinson's disease (PD). However, subtle features of early disease stages may be missed. Methods: We studied 25 early PD patients using a newly compiled battery of motor tests focusing on subtle motor features. Focal dystonia patients (n = 31) and healthy individuals (n = 26) served as controls. Specifically, asymmetric shoulder null position and delayed shoulder shrugs, reduced arm swing, subtle tremor, and timed finger taps were assessed. Spiral drawings and writing were also studied. Results: With a total mean of 9.8 ± 4.9 (possible range: 0-94), PD patients scored significantly higher than dystonia patients (2.9 ± 2.0) and healthy controls (1.9 ± 2.0) (P < 0.001). Reduced arm swing and tremor of individual fingers best distinguished PD from the other groups. Conclusions: The battery was sensitive to detect subtle motor features missed by the UPDRS. For future revisions of an international motor score, further assessment of these items may be worthwhile.

Affiliations:

Allemagne

Links toward previous steps (curation, corpus...)

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to stream Main, to step Curation: 001224

Le document en format XML

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<front><div type="abstract" xml:lang="en">Background: The UPDRS is the most widely used rating scale for Parkinson's disease (PD). However, subtle features of early disease stages may be missed. Methods: We studied 25 early PD patients using a newly compiled battery of motor tests focusing on subtle motor features. Focal dystonia patients (n = 31) and healthy individuals (n = 26) served as controls. Specifically, asymmetric shoulder null position and delayed shoulder shrugs, reduced arm swing, subtle tremor, and timed finger taps were assessed. Spiral drawings and writing were also studied. Results: With a total mean of 9.8 ± 4.9 (possible range: 0-94), PD patients scored significantly higher than dystonia patients (2.9 ± 2.0) and healthy controls (1.9 ± 2.0) (P < 0.001). Reduced arm swing and tremor of individual fingers best distinguished PD from the other groups. Conclusions: The battery was sensitive to detect subtle motor features missed by the UPDRS. For future revisions of an international motor score, further assessment of these items may be worthwhile.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

A Study of Subtle Motor Signs in Early Parkinson's Disease

A Study of Subtle Motor Signs in Early Parkinson's Disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri